Lung Cancer for Smokers and Non-Smokers May Be Different
A study conducted by Kelsie Thu, a doctoral candidate at the British Columbia Cancer Research Center in Vancouver, suggested that lung cancer in smokers and non-smokers may be two different diseases, as shared in a feature on Bloomberg Business Week.
Thu was quoted in the feature: “If we find out lung cancer in never-smokers is a different disease and we can identify what those differences are, maybe we can design specific therapies that target the genetic alterations in never-smokers and improve the prognosis.”
In her research, Thu found that the tumors in patients who had never smoked had two times as many DNA abnormalities as patients who had either smoked in the past, or were current smokers. These were the results yielded by a comparison of tumors in 30 patients who were non-smokers, against tumors in 53 patients who had a history of smoking.
The American Cancer Society identified lung cancer as the leading cause of cancer deaths in the United States, regardless of the gender. Despite the fact that it is a disease associated mainly to smoking, both smokers and non-smokers can acquire the disease.
Previous studies have already found indications that there is a difference between tumors in smokers and non-smokers. Thu’s research served as further confirmation of a previous finding that patients with no history of smoking are more likely to have epidermal growth factor receptor (EGFR) mutation.
Thu is scheduled to present her findings at the annual conference of the American Association of Cancer Research, in Philadelphia, on Monday.Tags: lung cancer, non smokers lung cancer, smoker's lung, smokers lung cancer